![]() One or both of these supplements may be beneficial in the treatment of anxiety and/or depression. The amino acid theanine is an antagonist to glutamate, an excitatory neurotransmitter. The amino acid taurine is a precursor to GABA, an inhibitory neurotransmitter. Thus, “targeted amino acid therapy” with one or more of the above supplements may alleviate the symptoms of depression and/or anxiety in some individuals. ![]() The amino acids tryptophan and 5-HTP are precursors to serotonin, which in turn is a precursor to melatonin the amino acids phenylalanine and tyrosine are precursors to dopamine, which in turn is a precursor to norepinephrine. Just as many prescription drugs are hypothesized to treat anxiety or depression by restoring balance at a neurotransmitter level, certain supplements may do the same. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.Anxiety and depression may arise from imbalances in neurotransmitters, such as serotonin, norepinephrine, dopamine, GABA, and glutamate. The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. This is particularly important when the recommended agent is a new and/or infrequently employed drug.ĭisclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). ![]() However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.ĭrug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. Taken together, these results suggest that taurine could be beneficial for the control of anxiety in the clinical situations.Ĭopyright: All rights reserved. It did not alter memory function and muscle activity. Taurine’s action could be due to its binding to and activating of strychnine-sensitive glycine receptor in vivo as it inhibited convulsion caused by strychnine however, it has little effect on picrotoxin-induced convulsion, suggesting its anti-anxiety activity may not be linked to GABA receptor. ![]() Taurine (200 mg/kg, p.o.) significantly reduced rearing numbers in the staircase test while it increased the time spent in the open arms as well as the number of entries to the open arms in the elevated plus maze test, suggesting that it has a significant anti-anxiety activity. The Rotarod test was performed to test muscle relaxant activity and the passive avoidance test was carried out to test memory activity in response to taurine. Convulsions induced by strychnine, picrotoxin, yohimbine and isoniazid were tested to explore the mechanism of anti-anxiety activity of taurine. The staircase test and elevated plus maze test were performed to test the anti-anxiety action of taurine. In the present study, we tested to see whether taurine exerts anti-anxiety effects and to explore its mechanism of anti-anxiety activity in vivo. However, its action in the central nervous system remains to be characterized. Taurine has a variety of actions in the body such as cardiotonic, host-defensive, radioprotective and glucose-regulatory effects.
0 Comments
Leave a Reply. |